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Representation-driven Endoscopic Visual Embedding Alignment for Latent Generation

arXiv cs.CV Medical/Healthcare AI Francisco Caetano, Tim J. M. Jaspers, Haiko Middeljans, Martijn R. Jong, Rixta A. H. van Eijck van Heslinga, Floor Slooter, Albert J. de Groof, Jacques J. Bergman, Peter H. N. De With, Fons van der Sommen 2026-08-07
Representative image for Representation-driven Endoscopic Visual Embedding Alignment for Latent Generation

TL;DR - REVEAL is a diffusion-transformer generative foundation model for endoscopy, trained on GastroNet-5M (5M multicenter frames), that aligns diffusion latents with in-domain endoscopic encoders instead of out-of-domain priors. It matters because it cuts the compute barrier to building specialized clinical imaging tools while doubling as a strong feature extractor.

  • Uses representation alignment with encoders pretrained on the endoscopic distribution, arguing out-of-domain priors fail to preserve fine textures and anatomical structure in this specialized image space.
  • Claimed to be the largest endoscopy generative foundation model to date; trained on the multicenter GN-5M dataset of 5 million frames.
  • As a feature extractor it is competitive with, and sometimes exceeds, classification-tuned endoscopic foundation models (EndoViT, Endo-FM), with reported robustness under realistic imaging corruptions.
  • Supports high-fidelity synthesis plus latent-space edits (inpainting, outpainting) with structural coherence, and is positioned as a backbone for conditional synthesis, segmentation, and OOD detection.

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