AIVC只是前菜!复旦提出生命算子,统一生命建模
TL;DR - Fudan and HKUST researchers propose “Life Operators,” a preprint framework for composing AI and mechanistic models across cells, tissues, organs, and whole-body observations. It aims to support testable simulations of disease progression and treatment effects rather than merely reproducing biological appearance.
- The framework defines perception operators to infer latent biological states, evolution operators to predict dynamics and interventions, and generation operators to produce observable clinical outcomes.
- A “Scale Bridge” passes task-relevant parameters, boundary conditions, and probabilistic constraints between biological scales, assembling selected components into a Life Operator Graph.
- Operators are intended to evolve only through independent data, prospective studies, or experimental validation, with insufficiently supported versions restricted or retired.
- The team is prototyping the approach in Cardio-World, a cross-scale cardiac system targeting virtual evaluation of drugs, devices, and personalized treatments.