Genetic associations with the Big Five personality traits probed in one million people

TL;DR - A million-person genetic study links hundreds of DNA variants to the Big Five personality traits, helping explain their moderate heritability. The findings suggest robust but complex biological pathways with broad relevance to health and socioeconomic outcomes.

• The analysis examines genetic associations with differences in how people think, feel, and act.
• Hundreds of genetic variants contribute to the Big Five traits; no single variant is presented as determinative.
• The pathways connecting DNA to personality are widespread and complex.
• These associations could inform research on personality’s links to health, wealth, work, and relationships.