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Do Pathology Vision-Language Models Truly See Pathology?

arXiv cs.CV Medical/Healthcare AI Chengyang Zhang, Wenchuan Zhang, Bo Li, Xinyu Liu, Jiaming Yang, Mengran Li, Chenxun Deng, Jie Chen, Yang Zhang, Wei Ju, Yuhao Yi, Hong Bu, Jiancheng Lv 2026-07-23

TL;DR - PathBind is a 2,600-sample benchmark testing whether pathology vision-language models genuinely connect answers to visual evidence. Results reveal a substantial gap between VQA accuracy and visual-semantic grounding.

  • Gemini-3-Pro averaged 53.5% across five pathology VQA benchmarks without visual input, exposing textual shortcuts.
  • Domain training improved accuracy without proportional visual binding gains; Patho-R1-7B underperformed Qwen2.5-VL-7B on multimodal gain and attention IoU.
  • Entity-level attention was diffuse and weakly query-specific on PathVG.
  • Evaluations covered 18 VLMs on VQA and 10 on region-level grounding.

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