Spike inference from calcium imaging data acquired with GCaMP8 indicators

TL;DR - This Nature Methods analysis examines spike inference from GCaMP8 calcium-imaging data across multiple algorithms. It highlights indicator linearity as an important factor in recovering neural spike activity.

• Compares spike-inference behavior across several GCaMP8 variants.
• Evaluates multiple inference algorithms.
• Emphasizes how indicator linearity affects the inference process.