Fly neurons carry a molecular ‘timestamp’ that encodes their birth order
Merged summary
TL;DR - A single-cell gene-expression atlas mapped onto the fruit-fly nerve cord’s wiring diagram revealed a shared molecular code that records neurons’ birth order. This “timestamp” helps explain how developmental lineage shapes neuronal diversity.
- Integrates single-cell gene-expression data with neural connectivity.
- Identifies a gene-expression code shared across neurons.
- The code preserves the order in which neurons arose from a parent cell.
- Birth-order information contributes to neuronal diversification.
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Fly neurons carry a molecular ‘timestamp’ that encodes their birth order
TL;DR - A single-cell gene-expression atlas mapped onto the fruit-fly nerve cord’s wiring diagram revealed a shared molecular code that records neurons’ birth order. This “timestamp” helps explain how developmental lineage shapes neuronal diversity.
- Integrates single-cell gene-expression data with neural connectivity.
- Identifies a gene-expression code shared across neurons.
- The code preserves the order in which neurons arose from a parent cell.
- Birth-order information contributes to neuronal diversification.