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Toward Generalizable Cognitive Impairment Detection with Speech-Based Multimodal Large Language Models

Research Medical/Healthcare AI

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TL;DR - A privacy-preserving multimodal framework combines speech acoustics and transcripts using open-source LLMs to detect cognitive impairment. It reports 92.4% accuracy and improved cross-dataset generalization, supporting scalable, non-invasive screening.

  • Extracts acoustic embeddings from speech and textual embeddings from automatic transcripts.
  • Concatenates modality-specific embeddings for classification without downstream access to raw patient data.
  • Evaluated on the ADReSS20 and ADReSSo21 benchmark datasets.
  • Consistently outperforms single-modality baselines and reports state-of-the-art cognitive-impairment identification.

Sources (1)

Toward Generalizable Cognitive Impairment Detection with Speech-Based Multimodal Large Language Models

arXiv eess.SP Yingchao Huang, Xin Wang, Yuhan Su, Shanshan Yao 2026-07-23 arXiv:2607.21496
Public signals Semantic Scholar citations 0 · Semantic Scholar influential citations 0
Providers: Hugging Face · N/A OpenAlex · N/A Publisher · N/A Semantic Scholar · Citations 0 · Influential citations 0 X · N/A Fetched 2026-08-15 14:29:56.252158 UTC

TL;DR - A privacy-preserving multimodal framework combines speech acoustics and transcripts using open-source LLMs to detect cognitive impairment. It reports 92.4% accuracy and improved cross-dataset generalization, supporting scalable, non-invasive screening.

  • Extracts acoustic embeddings from speech and textual embeddings from automatic transcripts.
  • Concatenates modality-specific embeddings for classification without downstream access to raw patient data.
  • Evaluated on the ADReSS20 and ADReSSo21 benchmark datasets.
  • Consistently outperforms single-modality baselines and reports state-of-the-art cognitive-impairment identification.
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