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Interpretable EEG biomarkers with bag-of-waves: Spatial and temporal waveform dictionaries for low-data regimes

Research Medical/Healthcare AI

Merged summary

TL;DR - Bag-of-waves learns interpretable dictionaries of recurring EEG waveforms and uses their frequencies and transitions for classification or clustering. It matches strong deep and foundation-model baselines across three datasets while remaining compact and effective with limited data.

  • Uses unsupervised shift-invariant k-means to convert continuous EEG into inspectable waveform “atom” tokens.
  • Captures temporal structure with atom n-grams and spatial structure with regional and cross-channel atoms.
  • Evaluated on mouse genotype clustering, dementia classification, and six-way clinical event classification.
  • Recovers known clinical waveform morphologies that neurophysiologists can directly validate.

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Interpretable EEG biomarkers with bag-of-waves: Spatial and temporal waveform dictionaries for low-data regimes

arXiv cs.LG Athanasios Papastathopoulos-Katsaros, Steven T. Lee, Lin Yao, Ajay Thomas, Junseok Park, Matthew J. McGinley, Zhandong Liu 2026-07-24 arXiv:2607.22508

TL;DR - Bag-of-waves learns interpretable dictionaries of recurring EEG waveforms and uses their frequencies and transitions for classification or clustering. It matches strong deep and foundation-model baselines across three datasets while remaining compact and effective with limited data.

  • Uses unsupervised shift-invariant k-means to convert continuous EEG into inspectable waveform “atom” tokens.
  • Captures temporal structure with atom n-grams and spatial structure with regional and cross-channel atoms.
  • Evaluated on mouse genotype clustering, dementia classification, and six-way clinical event classification.
  • Recovers known clinical waveform morphologies that neurophysiologists can directly validate.
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