体重减了，头却秃了？华人团队顶刊研究证实：司美格鲁肽等GLP-1类药物，增加脱发风险
Merged summary
TL;DR - A BMJ target-trial emulation found GLP-1 receptor agonists were associated with increased non-scarring hair-loss risk in adults with type 2 diabetes, though the absolute risk remained low.
- Electronic health records compared GLP-1 initiators with users of SGLT-2 and DPP-4 inhibitors.
- Relative hair-loss risk was 37% higher versus SGLT-2 inhibitors and 68% higher versus DPP-4 inhibitors.
- Absolute rates were 6.9, 5.0, and 3.9 cases per 1,000 person-years, respectively.
- Hair loss clustered within the first treatment year and may relate to weight loss, caloric deficits, and nutritional changes.
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体重减了，头却秃了？华人团队顶刊研究证实：司美格鲁肽等GLP-1类药物，增加脱发风险
TL;DR - A BMJ target-trial emulation found GLP-1 receptor agonists were associated with increased non-scarring hair-loss risk in adults with type 2 diabetes, though the absolute risk remained low.
- Electronic health records compared GLP-1 initiators with users of SGLT-2 and DPP-4 inhibitors.
- Relative hair-loss risk was 37% higher versus SGLT-2 inhibitors and 68% higher versus DPP-4 inhibitors.
- Absolute rates were 6.9, 5.0, and 3.9 cases per 1,000 person-years, respectively.
- Hair loss clustered within the first treatment year and may relate to weight loss, caloric deficits, and nutritional changes.