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Intestinal stem cells count to eight divisions to maintain cell ratios

Research Stem Cell Biology

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TL;DR - Fly intestinal stem cells maintain cell-type ratios through a division-counting program: eight rounds produce absorptive cells, followed by one round producing secretory cells.

  • The study examines stem-cell behavior in the fly gut.
  • Division count determines which cell type is produced.
  • The eight-to-one schedule preserves the balance between absorptive and secretory cells.

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Intestinal stem cells count to eight divisions to maintain cell ratios

Nature Joaquín de Navascués 2026-07-29 doi:10.1038/d41586-026-02128-w
Public signals OpenAlex citations 0
Providers: Hugging Face · N/A OpenAlex · Citations 0 Publisher · N/A Semantic Scholar · N/A X · N/A Fetched 2026-08-28 14:31:56.146146 UTC

TL;DR - Fly intestinal stem cells maintain cell-type ratios through a division-counting program: eight rounds produce absorptive cells, followed by one round producing secretory cells.

  • The study examines stem-cell behavior in the fly gut.
  • Division count determines which cell type is produced.
  • The eight-to-one schedule preserves the balance between absorptive and secretory cells.
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