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Region-Grounded Vision-Language Learning for Detection-Guided Mammographic Lesion Classification

Research Medical/Healthcare AI

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TL;DR - A region-grounded vision-language method for mammographic lesion classification that aligns localized lesion features with clinical text descriptors, mirroring how radiologists work. It matters because standard whole-image contrastive alignment dilutes the small, subtle lesion cues critical for malignancy assessment.

  • Region-text contrastive pretraining aligns lesion-specific features with structured clinical descriptors from radiology metadata, rather than aligning at the whole-image level.
  • Multi-component objective combats semantic collapse and background bias in low-vocabulary settings via positive alignment, fine-grained semantic hard negatives, and background suppression.
  • Auxiliary lesion detection head is jointly optimized with contrastive classification to preserve spatial sensitivity and enable localization-aware malignancy classification.
  • Evaluated on CBIS-DDSM and VinDr-Mammo, reporting superior performance vs. related methods across in-domain, cross-dataset, and transfer-learning settings (specific metrics not provided).

Sources (1)

Region-Grounded Vision-Language Learning for Detection-Guided Mammographic Lesion Classification

arXiv cs.CV Zhengbo Zhou, Jiren Li, Dooman Arefan, Margarita Zuley, Shandong Wu 2026-07-17 arXiv:2607.15615
Public signals Semantic Scholar citations 0 · Semantic Scholar influential citations 0
Providers: Hugging Face · N/A OpenAlex · N/A Publisher · N/A Semantic Scholar · Citations 0 · Influential citations 0 X · N/A Fetched 2026-08-18 14:39:31.567238 UTC

TL;DR - A region-grounded vision-language method for mammographic lesion classification that aligns localized lesion features with clinical text descriptors, mirroring how radiologists work. It matters because standard whole-image contrastive alignment dilutes the small, subtle lesion cues critical for malignancy assessment.

  • Region-text contrastive pretraining aligns lesion-specific features with structured clinical descriptors from radiology metadata, rather than aligning at the whole-image level.
  • Multi-component objective combats semantic collapse and background bias in low-vocabulary settings via positive alignment, fine-grained semantic hard negatives, and background suppression.
  • Auxiliary lesion detection head is jointly optimized with contrastive classification to preserve spatial sensitivity and enable localization-aware malignancy classification.
  • Evaluated on CBIS-DDSM and VinDr-Mammo, reporting superior performance vs. related methods across in-domain, cross-dataset, and transfer-learning settings (specific metrics not provided).
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