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Neural Transport Nested Sampling

Research Molecular Sampling

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TL;DR - Neural Transport Nested Sampling combines nested sampling with flow-guided, Metropolis–Hastings-corrected Langevin dynamics to sample molecular Boltzmann distributions and estimate partition functions. It improves sampling accuracy and cost on challenging particle systems while recovering temperature-dependent phase structure from one run.

  • Requires only evaluations of the target energy function.
  • Scales to Lennard–Jones clusters containing 55 interacting particles.
  • Reduces interatomic-distance and energy Wasserstein errors by over an order of magnitude versus the strongest neural baselines, at lower wall-clock cost.
  • Produces calibrated, temperature-resolved partition-function estimates at a scale the authors report as unprecedented for neural samplers.

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Neural Transport Nested Sampling

arXiv cs.LG David Yallup, Will Handley 2026-09-24 arXiv:2609.29413
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Providers: Hugging Face · N/A OpenAlex · N/A Publisher · N/A Semantic Scholar · N/A X · N/A Fetched 2026-09-26 14:13:31.931408 UTC

TL;DR - Neural Transport Nested Sampling combines nested sampling with flow-guided, Metropolis–Hastings-corrected Langevin dynamics to sample molecular Boltzmann distributions and estimate partition functions. It improves sampling accuracy and cost on challenging particle systems while recovering temperature-dependent phase structure from one run.

  • Requires only evaluations of the target energy function.
  • Scales to Lennard–Jones clusters containing 55 interacting particles.
  • Reduces interatomic-distance and energy Wasserstein errors by over an order of magnitude versus the strongest neural baselines, at lower wall-clock cost.
  • Produces calibrated, temperature-resolved partition-function estimates at a scale the authors report as unprecedented for neural samplers.
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