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How smallpox reached the Americas: first genomic evidence points to Europeans

Nature Ancient Pathogen Genomics Freda Kreier 2026-07-31

TL;DR - Viral sequences recovered from Chilean mummies provide the first genomic evidence that smallpox reached the Americas from Europe. The finding clarifies the disease’s historical origin and spread.

  • Ancient viral DNA links the detected smallpox infections to European introduction.
  • The evidence comes from genomic analysis of Chilean mummified remains.
  • The provided summary does not specify sample dates, sequencing methods, or phylogenetic details.

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