Phosphine-mediated azine C–H couplings with water and ammonia

TL;DR - This Nature paper reports phosphine-mediated C–H coupling of azines with water and ammonia. Based on the title alone, it suggests a synthetic route for incorporating oxygen- or nitrogen-derived functionality, but specific results are not provided.

• Published online in Nature on 11 August 2026.
• Focuses on direct azine C–H bond functionalization.
• Uses water and ammonia as coupling partners under phosphine-mediated conditions.
• The supplied content does not include reaction scope, mechanism, yields, or limitations.