Reply to: Artefacts in single-cell mtDNA analyses misinform phylogenies

TL;DR - This Nature item is a formal reply concerning whether artefacts in single-cell mitochondrial DNA analyses lead to incorrect phylogenies. Because only the title and publication metadata are provided, the reply’s arguments and conclusions cannot be determined.

• Published online in Nature on 19 August 2026.
• Focuses on methodological reliability in single-cell mtDNA-based phylogenetic analysis.
• The title indicates a response within a scientific debate about analysis artefacts.
• No experimental results, methods, or supporting evidence are included in the provided content.