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Life-inspired interoceptive artificial intelligence for autonomous and adaptive agents

Nature Machine Intelligence LLM Agents Sungwoo Lee, Younghyun Oh, Hyunhoe An, Hyebhin Yoon, Karl J. Friston, Seok Jun Hong, Choong-Wan Woo 2026-08-26

TL;DR - Lee, Oh et al. propose interoception—the biological capacity to sense and respond to internal states—as a framework for developing more autonomous and adaptive AI agents. The work matters as a life-inspired direction for agents that regulate and adjust their own behavior.

  • Draws design principles from how living organisms monitor internal conditions.
  • Frames interoception as a foundation for agent autonomy and adaptation.
  • Proposes a conceptual framework; no specific experimental results are provided in the excerpt.

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