Ultrafast and reference-free sequence discovery in single-cell data

TL;DR - Malva is a method for ultrafast, reference-free discovery of raw sequences in single-cell datasets spanning millions of cells. It could turn static transcriptomic atlases into searchable resources for investigating sequence function.

• Searches raw single-cell sequences without requiring a reference sequence.
• Scales sequence discovery across millions of cells.
• Enables dynamic querying of large transcriptomic atlases.
• The provided abstract does not specify benchmarks, implementation details, or biological findings.