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Imaging cellular activity across all organs reveals body-wide circuits

Nature Cellular Imaging Virginie M. S. Ruetten, Wei Zheng, Igor Siwanowicz, Brett D. Mensh, Mark Eddison, Amy Hu, Yunfeng Chi, Andrew L. Lemire, Caiying Guo, Mykola Kadobianskyi, Marc Renz, Sara Lelek-Greskovic, Yisheng He, Kari Close, Gudrun Ihrke, Aparna Dev, Alyson Petruncio, Yinan Wan, Rongwei Zhang, Mark C. Fishman, Florian Engert, Benjamin Judkewitz, Mikail Rubinov, Philipp J. Keller, Chie Satou, Guoqiang Yu, Paul W. Tillberg, Maneesh Sahani, Misha B. Ahrens 2026-09-09

TL;DR - Researchers developed a whole-body imaging system that records cellular activity across all zebrafish organs. It enables simultaneous observation of organ dynamics and reveals distributed circuits spanning the body.

  • Captures cellular activity throughout the entire zebrafish body.
  • Records dynamics across multiple organs within a unified imaging framework.
  • Identifies multiple distributed, body-wide cellular circuits.
  • The provided summary does not specify the imaging modality, resolution, or individual circuits discovered.

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