When a laser beam hits an electron beam

TL;DR - Specially engineered transmission electron microscope prototypes use laser–electron beam interactions to substantially improve image contrast for cryo-EM and cryo-ET. This could make structural and tomographic imaging more informative, though the provided summary does not report quantitative results.

• The work focuses on prototype transmission electron microscopes with specialized engineering.
• Their key advance is greatly improved contrast in cryo-EM and cryo-ET images.
• Better contrast could aid visualization in structural biology and cellular tomography.
• No specific performance metrics, biological applications, or deployment details are provided.