Landmark map of human brain’s gene activity holds clues to Alzheimer’s disease and more

TL;DR - Researchers created a large atlas of gene activity in the human prefrontal cortex using samples from nearly 1,500 donors spanning infancy to more than 100 years old. The resource could help reveal how gene expression changes across the lifespan and provide clues to Alzheimer’s disease and other brain conditions.

• Maps gene expression in the prefrontal cortex, a region central to higher cognitive functions.
• Covers an unusually broad age range, from infants to centenarians.
• Draws on samples from almost 1,500 donors.
• The provided excerpt does not specify the atlas’s methods or disease-related findings.