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Brown bullhead catfish melanoma represents a novel transmissible cancer

Nature Cancer Genomics Emily E. Curd, Samuel F. M. Hart, James Lubkowitz, Kirsten M. Tracy, Lucas Milazzo, Matthew Bodnar, Tom Jones, Mark J. Henderson, Peter Emerson, Julie A. Dragon 2026-07-22

TL;DR - Whole-genome sequencing of brown bullhead catfish tumours and matched healthy tissues identifies a naturally occurring transmissible cancer. This expands the known range of cancers capable of spreading between individuals.

  • The study compares tumour genomes with matched non-tumour host tissue.
  • Genomic evidence indicates the melanoma is a distinct transmissible cancer lineage.
  • The finding provides a new model for studying cancer transmission and evolution in wildlife.

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