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Brown bullhead catfish melanoma represents a novel transmissible cancer

Research Cancer Genomics

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TL;DR - Whole-genome sequencing of brown bullhead catfish tumours and matched healthy tissues identifies a naturally occurring transmissible cancer. This expands the known range of cancers capable of spreading between individuals.

  • The study compares tumour genomes with matched non-tumour host tissue.
  • Genomic evidence indicates the melanoma is a distinct transmissible cancer lineage.
  • The finding provides a new model for studying cancer transmission and evolution in wildlife.

Sources (1)

Brown bullhead catfish melanoma represents a novel transmissible cancer

Nature Emily E. Curd, Samuel F. M. Hart, James Lubkowitz, Kirsten M. Tracy, Lucas Milazzo, Matthew Bodnar, Tom Jones, Mark J. Henderson, Peter Emerson, Julie A. Dragon 2026-07-22 doi:10.1038/s41586-026-10828-6
Public signals OpenAlex citations 4
Providers: Hugging Face · N/A OpenAlex · Citations 4 Publisher · N/A Semantic Scholar · N/A X · N/A Fetched 2026-08-21 14:37:54.850905 UTC

TL;DR - Whole-genome sequencing of brown bullhead catfish tumours and matched healthy tissues identifies a naturally occurring transmissible cancer. This expands the known range of cancers capable of spreading between individuals.

  • The study compares tumour genomes with matched non-tumour host tissue.
  • Genomic evidence indicates the melanoma is a distinct transmissible cancer lineage.
  • The finding provides a new model for studying cancer transmission and evolution in wildlife.
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