A radical approach to making C-glycoside molecules

TL;DR - Researchers developed a platform for synthesizing C-glycosides from sugars using glycosyl sulfonyl hydrazides as accessible free-radical precursors. It enables targeted, stereospecific carbon–carbon bond formation across carbohydrate scaffolds.

• Uses readily accessible glycosyl sulfonyl hydrazides to generate free radicals.
• Forms robust carbon–carbon linkages in C-glycoside molecules.
• Controls the desired 3D arrangement of atoms during synthesis.
• Offers a general strategy for constructing valuable carbohydrate-derived compounds.