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Same Branches, Different Trees: A Bifurcation Connectedness Metric for Coronary Artery Segmentation and FFR-CT Decision Agreement

Research Medical/Healthcare AI

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TL;DR - This paper proposes the Bifurcation Connectedness Score (BCS) for coronary artery segmentation, measuring vessel-tree connectivity that overlap metrics can miss. Better BCS correlates with closer FFR-CT treatment-decision agreement, especially in severe disease.

  • BCS evaluates connectivity at each ground-truth bifurcation and strongly detects localized vessel breaks.
  • It remains largely stable under narrowing that preserves connectivity, distinguishing topology from volumetric overlap.
  • Higher BCS was associated with better predicted-versus-ground-truth FFR-CT decision agreement in severe disease (OR 2.16, CI [1.23, 4.18]).
  • Soft-BCS provides a differentiable training surrogate; results suggest branch recovery and branch connectivity should be reported separately.

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Same Branches, Different Trees: A Bifurcation Connectedness Metric for Coronary Artery Segmentation and FFR-CT Decision Agreement

arXiv cs.CV Maame Owusu-Ansah, Kelvin Lee, Dr Vinod Venugopal, Muhammad Moazzam Jawaid, Wenting Duan, James Brown 2026-07-30 arXiv:2607.28327
Public signals Semantic Scholar citations 0 · Semantic Scholar influential citations 0
Providers: Hugging Face · N/A OpenAlex · N/A Publisher · N/A Semantic Scholar · Citations 0 · Influential citations 0 X · N/A Fetched 2026-08-18 14:29:12.885504 UTC

TL;DR - This paper proposes the Bifurcation Connectedness Score (BCS) for coronary artery segmentation, measuring vessel-tree connectivity that overlap metrics can miss. Better BCS correlates with closer FFR-CT treatment-decision agreement, especially in severe disease.

  • BCS evaluates connectivity at each ground-truth bifurcation and strongly detects localized vessel breaks.
  • It remains largely stable under narrowing that preserves connectivity, distinguishing topology from volumetric overlap.
  • Higher BCS was associated with better predicted-versus-ground-truth FFR-CT decision agreement in severe disease (OR 2.16, CI [1.23, 4.18]).
  • Soft-BCS provides a differentiable training surrogate; results suggest branch recovery and branch connectivity should be reported separately.
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