Amplifying multiplex spatial profiling with tyramide oligonucleotides
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TL;DR - PASTA is a method for integrating and amplifying protein and nucleic-acid signals in imaging-based spatial biology. It could make multiplex spatial profiling more flexible across assay types.
- Uses tyramide oligonucleotide conjugates for signal amplification.
- Supports both protein and nucleic-acid spatial measurements.
- Works with diverse assays that use horseradish peroxidase readout.
- Enables serial amplification and integration of multiple signals.
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Amplifying multiplex spatial profiling with tyramide oligonucleotides
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TL;DR - PASTA is a method for integrating and amplifying protein and nucleic-acid signals in imaging-based spatial biology. It could make multiplex spatial profiling more flexible across assay types.
- Uses tyramide oligonucleotide conjugates for signal amplification.
- Supports both protein and nucleic-acid spatial measurements.
- Works with diverse assays that use horseradish peroxidase readout.
- Enables serial amplification and integration of multiple signals.