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Beyond Endpoint Gains: A Weight-Delta Audit of Medical Specialization

Research Medical/Healthcare AI

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TL;DR - This paper audits the weight changes between general-purpose LLMs and their medical-specialized counterparts, finding that decoder updates closely reproduce benchmark gains but do not yield a simple component-level explanation of specialization.

  • Examines aligned Gemma-3-to-MedGemma and Qwen2.5-to-HuatuoGPT-o1 checkpoint pairs.
  • Full decoder deltas strongly reconstruct medical benchmark movement, with endpoint-normalized retention of 0.974 and 1.183.
  • MLP layers are the strongest broad component family in both pairs, but controls and rollback tests prevent uniquely attributing the gains to them.
  • Conclusions are limited to text-only multiple-choice benchmarks and do not establish clinical validity or circuit-level mechanisms.

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Beyond Endpoint Gains: A Weight-Delta Audit of Medical Specialization

arXiv cs.AI Praphul Singh, Shanu Kumar, Akshat Agarwal 2026-08-21 arXiv:2608.20768
Public signals Semantic Scholar citations 0 · Semantic Scholar influential citations 0
Providers: Hugging Face · N/A OpenAlex · N/A Publisher · N/A Semantic Scholar · Citations 0 · Influential citations 0 X · N/A Fetched 2026-09-22 14:32:54.654064 UTC

TL;DR - This paper audits the weight changes between general-purpose LLMs and their medical-specialized counterparts, finding that decoder updates closely reproduce benchmark gains but do not yield a simple component-level explanation of specialization.

  • Examines aligned Gemma-3-to-MedGemma and Qwen2.5-to-HuatuoGPT-o1 checkpoint pairs.
  • Full decoder deltas strongly reconstruct medical benchmark movement, with endpoint-normalized retention of 0.974 and 1.183.
  • MLP layers are the strongest broad component family in both pairs, but controls and rollback tests prevent uniquely attributing the gains to them.
  • Conclusions are limited to text-only multiple-choice benchmarks and do not establish clinical validity or circuit-level mechanisms.
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