A practical recycling strategy for making thiophosphate molecules with enzymes

TL;DR - Researchers developed an enzymatic platform for constructing thiophosphate molecular motifs while avoiding large quantities of expensive reagents. The approach could enable more practical enzymatic synthesis cascades for drug development.

• Uses enzymes to construct thiophosphate-containing molecules.
• Reduces reliance on costly reagents required in large amounts.
• Establishes a foundation for multi-step enzymatic synthesis of drug-relevant thiophosphate motifs.