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A practical recycling strategy for making thiophosphate molecules with enzymes

Research Biocatalytic Synthesis

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TL;DR - Researchers developed an enzymatic platform for constructing thiophosphate molecular motifs while avoiding large quantities of expensive reagents. The approach could enable more practical enzymatic synthesis cascades for drug development.

  • Uses enzymes to construct thiophosphate-containing molecules.
  • Reduces reliance on costly reagents required in large amounts.
  • Establishes a foundation for multi-step enzymatic synthesis of drug-relevant thiophosphate motifs.

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A practical recycling strategy for making thiophosphate molecules with enzymes

Nature 2026-08-26 doi:10.1038/d41586-026-02482-9
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Providers: Hugging Face · N/A OpenAlex · Citations 0 Publisher · N/A Semantic Scholar · N/A X · N/A Fetched 2026-09-25 14:26:39.245141 UTC

TL;DR - Researchers developed an enzymatic platform for constructing thiophosphate molecular motifs while avoiding large quantities of expensive reagents. The approach could enable more practical enzymatic synthesis cascades for drug development.

  • Uses enzymes to construct thiophosphate-containing molecules.
  • Reduces reliance on costly reagents required in large amounts.
  • Establishes a foundation for multi-step enzymatic synthesis of drug-relevant thiophosphate motifs.
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