Developmental xenocortication using human-derived organoids in mice
TL;DR - This Nature study develops “xenocortication,” using human-derived neural organoids to introduce human neurons into developing mouse cortical circuits. The approach enables circuit- and behaviour-level investigation of human neurodevelopment in vivo.
- Human-derived organoids provide the neurons used for xenocortication in mice.
- The model connects cellular neurodevelopment with circuit- and behavioural analysis.
- The supplied abstract does not specify experimental outcomes, disease applications, or quantitative results.