A multimodal, all-optical platform for linking cell identity to metabolic function in intact tissues
Ranking
Overall
84
Content
100
Popularity
46
Observed public metrics from 1 member.
Merged summary
TL;DR - REDCAT is an all-optical platform that connects cell identity with metabolic activity in intact tissues at single-cell and subcellular resolution. It could advance functional histopathology by revealing disease-associated metabolic changes and intratumoral heterogeneity.
- Integrates Raman imaging, autofluorescence, and high-plex immunofluorescence.
- Maps metabolic features alongside cellular identity without disrupting tissue structure.
- Resolved metabolic characteristics in normal lymph nodes and lipid-redox remodeling in lymphoma.
- Exposed metabolic heterogeneity within tumors, suggesting potential diagnostic and research applications.
Sources (1)
A multimodal, all-optical platform for linking cell identity to metabolic function in intact tissues
Public signals
OpenAlex citations 0
TL;DR - REDCAT is an all-optical platform that connects cell identity with metabolic activity in intact tissues at single-cell and subcellular resolution. It could advance functional histopathology by revealing disease-associated metabolic changes and intratumoral heterogeneity.
- Integrates Raman imaging, autofluorescence, and high-plex immunofluorescence.
- Maps metabolic features alongside cellular identity without disrupting tissue structure.
- Resolved metabolic characteristics in normal lymph nodes and lipid-redox remodeling in lymphoma.
- Exposed metabolic heterogeneity within tumors, suggesting potential diagnostic and research applications.