Vast cellular gene-expression atlas could transform how scientists understand brain ageing and disease
Ranking
Overall
72
Content
85
Popularity
42
Observed public metrics from 1 member.
Merged summary
TL;DR - A large single-nucleus RNA-sequencing atlas maps gene-expression changes in the human prefrontal cortex across ageing, health, and disease. It could help researchers identify cell-specific molecular patterns associated with brain ageing and disorders.
- Profiles gene expression at single-nucleus resolution, distinguishing changes among brain cell types.
- Spans the human lifespan and includes both healthy and disease contexts.
- Focuses on the prefrontal cortex, a region central to cognition and affected by ageing and neurological disease.
- The provided summary does not specify the atlas’s scale, disease cohorts, or individual molecular findings.
Sources (1)
Vast cellular gene-expression atlas could transform how scientists understand brain ageing and disease
Public signals
OpenAlex citations 0 · Semantic Scholar citations 0 · Semantic Scholar influential citations 0
TL;DR - A large single-nucleus RNA-sequencing atlas maps gene-expression changes in the human prefrontal cortex across ageing, health, and disease. It could help researchers identify cell-specific molecular patterns associated with brain ageing and disorders.
- Profiles gene expression at single-nucleus resolution, distinguishing changes among brain cell types.
- Spans the human lifespan and includes both healthy and disease contexts.
- Focuses on the prefrontal cortex, a region central to cognition and affected by ageing and neurological disease.
- The provided summary does not specify the atlas’s scale, disease cohorts, or individual molecular findings.